Cancer Nanomedicine Repository
Cancer is a complex and multifactorial disease and is highly difficult to treat. Traditional forms of therapy negatively affect healthy cells as well diseased ones. Nanoparticle drug delivery is a targeted form of therapy with promising potential. However delivery efficiency values across recently developed cancer nanoparticles remains low, therefore careful nanoparticle design is key.
The Cancer Nanoparticle Repository (CNR) is a web-based cumulative knowledge database bundled with a suite of statistical analysis tools. The CNR database contains published and peer-reviewed research data submitted by experts in the field cancer nanotechnology. CNR serves as an information resource and analytics support for the scientific community in search of optimising nanoparticle design for the purpose of cancer treatment.
Toronto General Hospital (BioBank)
Managing the development of a system for BioBank at Toronto General Hospital. The project involves using PHP, HTML and MySQL to create a web-based system that organises sample processing requests. It requires two web front-ends:
(1) A web form for the sample requester that processes the data and stores it within the database
(2) An interactive summary page for the BioBank technicians that displays pertinent information and organises the requests.
Biodiversity describes the many varieties of life forms and subsequent variations found on Earth. Biodiversity measures the assortment of organisms that maybe present in Earth's many ecosystems. Typically, it has been observed that biodiversity differs from the North and South Poles to tropical areas. This is referred to as the latitudinal diversity gradient and is one of the most widely recognized patterns in ecology. Current evidence suggests that regions of lower latitudes (near the equator) have more biodiversity than regions at higher latitudes (temperate regions). Explaining that phenomenon of the latitudinal diversity gradient is one of the biggest challenges that biologists are currently facing.
TeMPuЯa is a bioinformatics tool written in R to organize populations by tropical and temperate environments in order to analyze the effect of differential rate of evolution by nucleotide substitution due to geographical distances for indicators in the environment or disease transmitters. This project was in collaboration with the University of Guelph - Biodiversity Institute of Ontario with Dr. Sarah Adamowicz. It uses Barcode of Life (BOLD) database to scrape the information to be used as input in order to do the analysis.
GenBank Genome Retrieval
Web-based form created to retrieve complete genome of the virus selected, parse the contents into various subcategories for user friendliness purpose and option to email the selected input to the user
Web-based Interface for Relational Database
A web-based interface was build by me which allows users to enter, modify and retrieve data from a specified relational database. Data is entered as either a using an HTML form entry for single entry or uploaded as .csv file for multiple entries.
Ensembl Genome Retrieval
Web-based form created to retrieve complete or partially selected genome of selected species from Ensembl, parse individual contents and display output to the users on the browser.